Impact of Probiotic Formula (Lacto-5X) on Constipation: Improvements in Gastrointestinal Symptoms, Gut Microbiome, and Metabolites.
- 2025-04-09
- RCT
- Journal of microbiology and biotechnology 35
- Yoo-Jeong Jin
- Young Jae Park
- Jieun Choi
- Myung-Soo Kim
- Uigi Min
- Jonghyun Lim
- Jooyeon Kang
- Do Yup Lee
- Byung-Yong Kim
- PubMed: 40223270
- DOI: 10.4014/jmb.2412.12056
- High evidence
At the 4-week endpoint, the Probiotic group had significant improvements in stool consistency, stool frequency, abdominal pain, and straining compared to the Placebo group. Satisfaction with bowel habits and improvement in overall intestinal health were significantly higher in the Probiotic group.
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes