Bifidobacterium lactis UABla-12 and Reduced Atopic Dermatitis Severity

• The impact of prebiotics, probiotics and synbiotics on the prevention and treatment of atopic dermatitis in children: an umbrella meta-analysis.

  • 2025-03-21
  • Systematic Review · n = 150
  • Frontiers in pediatrics 13
  • • Lifeng Wang
    • Lijuan Xu

  • PubMed: 40191649
  • DOI: 10.3389/fped.2025.1498965

  3 Insights on

  • Reduced Atopic Dermatitis Severity

  • High evidence

  The treatment significantly reduced SCORAD score (WMD = -3.75, 95% CI: -5.08 to -2.42).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• The efficacy and safety of oral microecological agents as add-on therapy for atopic dermatitis: A systematic review and meta-analysis of randomized clinical trials.

  • 2023-12
  • Review · n = 1,230
  • Clinical and translational allergy 13(12)
  • • Peiwen Xue
    • Haiyan Qin
    • Di Qin
    • Huilin Liu
    • Juan Li
    • Rongjiang Jin
    • Xianjun Xiao

  • PubMed: 38146806
  • DOI: 10.1002/clt2.12318

  2 Insights on

  • Reduced Atopic Dermatitis Severity

  • High evidence

  Compared with controls, oral MA as an add-on therapy was associated with significantly lower SCORAD scores (MD = -5.30, 95% CI -8.50, -1.55, p < 0.01, I2 = 81%).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes