Bifidobacterium lactis and Improved Cognitive Function

• Cognitive and Emotional Effect of a Multi-species Probiotic Containing Lactobacillus rhamnosus and Bifidobacterium lactis in Healthy Older Adults: A Double-Blind Randomized Placebo-Controlled Crossover Trial.

  • 2024-06-27
  • RCT
  • Probiotics and antimicrobial proteins 17(5)
  • • Cristofer Ruiz-Gonzalez
    • Diana Cardona
    • Lola Rueda-Ruzafa
    • Miguel Rodriguez-Arrastia
    • Carmen Ropero-Padilla
    • Pablo Roman

  • PubMed: 38935259
  • DOI: 10.1007/s12602-024-10315-2

  3 Insights on

  • Improved Cognitive Function

  • High evidence

  After the intervention, noticeable enhancements were observed in cognitive function (mean difference 1.90, 95% CI 1.09 to 2.70, p < 0.005), memory (mean difference 4.60, 95% CI 2.91 to 6.29, p < 0.005) by MMSE and digit task

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

• Oral Administration of Bifidobacterium lactis Ameliorates Cognitive Deficits in Mice Intracerebroventricularly Administered Amyloid Beta via Regulation the Activation of Mitogen-activated Protein Kinases.

  • 2024-05
  • Food science of animal resources 44(3)
  • • Jong Kyu Choi
    • Oh Yun Kwon
    • Seung Ho Lee

  • PubMed: 38765290
  • DOI: 10.5851/kosfa.2024.e5

  3 Insights on

  • Improved Cognitive Function

  • Low evidence

  Oral administration of live BL to intracerebroventricularly Aβ-injected mice significantly attenuated short- and long-term memory loss estimated using the Y-maze and Morris water maze tests.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes