Usefulness of Bifidobacterium longum BB536 in Elderly Individuals With Chronic Constipation: A Randomized Controlled Trial
- 2022-10-03
- RCT · n = 80
- American Journal of Gastroenterology 118(3)
- T. Takeda
- D. Asaoka
- S. Nojiri
- N. Yanagisawa
- Yuji Nishizaki
- T. Osada
- S. Koido
- A. Nagahara
- N. Katsumata
- T. Odamaki
- Jinzhong Xiao
- T. Ohkusa
- Nobuhiro Sato
- PubMed: 36216361
- DOI: 10.14309/ajg.0000000000002028
- High evidence
There was a significant difference and a tendency toward a difference in the changes from baseline on the stool frequency (P = 0.008) and failure of evacuation (P = 0.051) subscales
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- 5 × 10^10 colony-forming unit once daily