Bifidobacterium longum BB536 and Increased Neutrophil Bactericidal Activity

Doses used in studies

CFU/day: 100 billion (median 100 billion, IQR 100 billion–100 billion) — 1 study

Time to effect

Median: 3.3 months · IQR 3.3 months–3.3 months · Range 3.3 months–3.3 months — Reported in 1 of 1 study

1 of 1 paper

Effects of Bifidobacterium longum BB536 administration on influenza infection, influenza vaccine antibody titer, and cell-mediated immunity in the elderly.

2010-05-23
RCT
Bioscience, biotechnology, and biochemistry 74(5)
- Kazuyoshi Namba
- Michiko Hatano
- Tomoko Yaeshima
- Mitsunori Takase
- Kunihiko Suzuki

PubMed: 20460726
DOI: 10.1271/bbb.90749

5 Insights on

Increased Neutrophil Bactericidal Activity

High evidence
Elderly

In the P1 period, the NK cell activity and the bactericidal activity of the neutrophils were significantly higher at week 5 than to before BB536 administration.

Effect: Beneficial
Effect size: Moderate
Significant: Yes
Dose: 1 x 10^11 CFU daily