Bifidobacterium longum iVE-15 and Reduced Mortality Rate During Pathogen Challenge

• Isolation and characterization of a novel phage lysin active against Paenibacillus larvae, a honeybee pathogen.

  • 2015-08-12
  • Clinical Trial
  • Bacteriophage 5(4)
  • • Lucy LeBlanc
    • Sara Nezami
    • Diane Yost
    • Philippos Tsourkas
    • Penny S Amy

  • PubMed: 26904379
  • DOI: 10.1080/21597081.2015.1080787

  1 Insight on

  • Reduced Mortality Rate During Pathogen Challenge

  • Moderate evidence

  A single dose of PlyPalA rescued 75% of larvae infected with endospores, showing that it represents a powerful tool for future treatment of AFB.

  Effect

  Beneficial

  Effect size

  Large