Bifidobacterium longum MAK34B12L and Increased Hepatic Glycogen Storage

• The antidiabetic effects of Bifidobacterium longum subsp. longum BL21 through regulating gut microbiota structure in type 2 diabetic mice.

  • 2022-10-05
  • Clinical Trial
  • Food & Function 13(19)
  • • Junyu Hao
    • Yongli Zhang
    • Tao Wu
    • R. Liu
    • Wenjie Sui
    • Jiangu Zhu
    • S. Fang
    • Jieting Geng
    • M. Zhang

  • PubMed: 36056711
  • DOI: 10.1039/d2fo01109c

  7 Insights on

  • Increased Hepatic Glycogen Storage

  • Low evidence
  • Animal Study

  BL21 enhanced the anti-oxidative capacity, increased the hepatic glycogen content, and significantly decreased the gene expression levels of glucose-6-phosphatase (G6Pase) and phosphoenolpyruvate carboxykinase (PEPCK) in the livers of diabetic mice.

  Effect

  Beneficial

  Effect size

  Large