Bifidobacterium longum R0175 and Increased threshold for myoclonic seizures

• Influence of dietary supplementation with two distinct probiotic strains, Bifidobacterium longum R0175 and Lacticaseibacillus rhamnosus JB-1, on seizure susceptibility and valproate response: Behavioral and biochemical studies in mice.

  • 2026-05
  • Nutrition (Burbank, Los Angeles County, Calif.) 145
  • • Piotr Wlaź
    • Karolina Skonieczna-Żydecka
    • Adrian Wiater
    • Daniel Styburski
    • Małgorzata Majewska
    • Anna Boguszewska-Czubara
    • Elżbieta Wyska
    • Alan González-Ibarra
    • Nikola Gapińska
    • Dorota Luchowska-Kocot
    • Renata Żelazowska
    • Marcin Grąz
    • Katarzyna Socała

  • PubMed: 41576857
  • DOI: 10.1016/j.nut.2025.113083

  1 Insight on

  • Increased threshold for myoclonic seizures

  • Low evidence
  • Animal Study

  B. longum R0175 slightly increased the threshold for myoclonic seizures in the ivPTZ.

  Effect

  Beneficial

  Effect size

  Small