Bifidobacterium longum Rosell-175 and Reduced C-Reactive Protein Levels

• Probiotics Decrease C-Reactive Protein Levels in Depression Depending on Metabolic Syndrome Presence or Antidepressant Treatment - Secondary Results of a Randomized Clinical Trial.

  • 2025-10-29
  • RCT · n = 88
  • Current neuropharmacology 23
  • • Oliwia Gawlik Kotelnicka
    • Adam Wysokinski
    • Agata Gajewska
    • Karolina Czarnecka-Chrebelska
    • Karolina Kopacz
    • Anna Skowrońska
    • Ewa Pikus
    • Ewa Brzeziańska-Lasota
    • Dominik Strzelecki

  • PubMed: 41177800
  • DOI: 10.2174/011570159x371175251002220658

  3 Insights on

  • Reduced C-Reactive Protein Levels

  • High evidence

  Probiotic supplementation decreased the levels of C-reactive protein (CRP) compared to placebo by 21.3% with a small effect size (p = .047, d = .249).

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes