Bifidobacterium longum subsp. longum and Improved Treatment Safety

• A phase II clinical trial of Bifidobacterium longum subsp. longum BL21 for preventing acute radiation enteritis among pelvic radiotherapy patients.

  • 2025-11-10
  • Clinical Trial · n = 52
  • Frontiers in nutrition 12
  • • Yinyin Yang
    • Xuhao Gu
    • Chang Liu
    • Li Zou
    • Liwei Xie
    • Yulong Liu
    • Peifeng Zhao
    • Ye Tian
    • Shang Cai

  • PubMed: 41293184
  • DOI: 10.3389/fnut.2025.1626169

  3 Insights on

  • Improved Treatment Safety

  • High evidence

  The safety profile of BL21 during RT was favorable, and we did not observe any serious adverse events associated with BL21.

  Effect

  Beneficial

  Effect size

  Small