Bifidobacterium longum subsp. longum and Reduced Acute Radiation Enteritis Severity

• A phase II clinical trial of Bifidobacterium longum subsp. longum BL21 for preventing acute radiation enteritis among pelvic radiotherapy patients.

  • 2025-11-10
  • Clinical Trial · n = 52
  • Frontiers in nutrition 12
  • • Yinyin Yang
    • Xuhao Gu
    • Chang Liu
    • Li Zou
    • Liwei Xie
    • Yulong Liu
    • Peifeng Zhao
    • Ye Tian
    • Shang Cai

  • PubMed: 41293184
  • DOI: 10.3389/fnut.2025.1626169

  3 Insights on

  • Reduced Acute Radiation Enteritis Severity

  • High evidence

  Compared with our historical control data, these patients exhibited lower levels of ≥ grade 2 ARE and required fewer antidiarrheal medications... Most diarrhea cases were classified as grade 1

  Effect

  Beneficial

  Effect size

  Small