Bifidobacterium longum and Enhanced Beneficial Metabolite Production

• Bifidobacterium longum subsp. infantis B8762 modulates the infant gut-lung axis via microbial and metabolic reprogramming.

  • 2026-06
  • RCT · n = 115
  • Microbial pathogenesis 215
  • • Rui Ma
    • Bo Jia
    • Xiangyang Zhang
    • Zhixin Zhao
    • Feiyan Zhao
    • Min-Tze Liong
    • Adli Ali
    • Intan Juliana Abd Hamid
    • Taufiq Hidayat Hasan
    • Fahisham Taib
    • Zhihong Sun

  • PubMed: 41802657
  • DOI: 10.1016/j.micpath.2026.108431

  3 Insights on

  • Enhanced Beneficial Metabolite Production

  • High evidence

  Functionally, B8762 upregulated metabolic pathways involved in coenzyme A and L-tryptophan biosynthesis and enhanced predicted production of immunoregulatory metabolites including butyrate, inosine, and chenodeoxycholic acid.

  Effect

  Beneficial

  Effect size

  Moderate