Bifidobacterium and Reduced Th2 Cytokine Production

• Probiotics, Prebiotics and Other Dietary Supplements for Gut Microbiota Modulation in Celiac Disease Patients.

  • 2020-09-02
  • Review
  • Nutrients 12(9)
  • • Giovanni Marasco
    • Giovanna Grazia Cirota
    • Benedetta Rossini
    • Lisa Lungaro
    • Anna Rita Di Biase
    • Antonio Colecchia
    • Umberto Volta
    • Roberto De Giorgio
    • Davide Festi
    • Giacomo Caio

  • PubMed: 32887325
  • DOI: 10.3390/nu12092674

  6 Insights on

  • Reduced Th2 Cytokine Production

  • Moderate evidence
  • Rigorous Journal
  • Clinical

  Pivotal studies on the supplementation of GFD with probiotics, such as Bifidobacterium and Lactobacilli, reported a potential to restore gut microbiota composition and to pre-digest gluten in the intestinal lumen, reducing the inflammation associated with gluten intake, the intestinal permeability, and the cytokine and antibody production.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes