Association between Nutrition Protocol with Clostridium butyricum MIYAIRI 588 and Reduced Incidence of Clostridioides difficile Infection in Critically Ill Patients: A Single-Center, Before-and-After Study.
- 2022-06-01
- RCT · n = 1,802
- Surgical Infections 23(5)
- Takeaki Sato
- D. Kudo
- S. Kushimoto
- PubMed: 35647891
- DOI: 10.1089/sur.2022.030
- High evidence
- Large Human Trial
There were 14 (1.9%) patients with CDI in the control group and one (0.1%) patient in the protocol group (p < 0.01).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes