Clostridium butyricum and Reduced Incidence of Bacterial Pneumonia

• Oxygen-driven nebulization of Clostridium butyricum prevents drug-resistant bacterial pneumonia.

  • 2026-01-24
  • RCT · n = 310
  • Applied microbiology and biotechnology 110(1)
  • • Mei-Hua Zhan
    • Shuai-Hua Zhan
    • Hui-Qiang Han
    • Li-Na Kang
    • Xin-Gang Yang
    • A-Xia Chai

  • PubMed: 41580563
  • DOI: 10.1007/s00253-026-13716-1

  2 Insights on

  • Reduced Incidence of Bacterial Pneumonia

  • High evidence
  • Large Human Trial

  The incidence of pneumonia was 46.45% (72/155) in the control group, compared to only 1.97% (3/152) in the experimental group (relative risk = 23.54, 95%CI: 7.58-73.08).

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes