Microbiome Differences in Colorectal Cancer Patients and Healthy Individuals: Implications for Vaccine Antigen Discovery.
- 2024-12-13
- Review
- ImmunoTargets and therapy 13
- Gordon C Ibeanu
- Adekunle B Rowaiye
- Joy C Okoli
- Daniel U Eze
- PubMed: 39698218
- DOI: 10.2147/itt.s486731
- Low evidence
Numerous microbes, particularly bacteria and viruses, are significantly overrepresented in CRC tissues and have been shown to promote tumorigenesis by inducing inflammation and modulating the immune system. This makes them promising candidates for antigens in the development of CRC vaccines.
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes