Across 3 studies, all reported beneficial effects on gastrointestinal symptoms, with effect sizes ranging from small to moderate. The evidence is limited to systematic reviews and narrative reviews in athletic and general adult populations, with no dose or duration data available. The predominant effect size is mixed (small to moderate) across studies.
Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. None of the included studies reported statistical significance, and no dose, form, or duration data were extracted, limiting the specificity of findings. The beneficial effects are drawn from broad probiotic reviews that include multiple strains, so the independent effect of Enterococcus faecium R0026 specifically is not isolated. Available evidence is overwhelmingly positive — publication bias may overstate benefits (null-result studies less likely to be indexed).
Only slight evidence was found for a positive effect of probiotics on GI symptoms in athletes during training, exercise, and competition
probiotics have a beneficial effect on mental health, cognitive functions, sleep, gastrointestinal, and upper respiratory symptoms in adult humans.
studies that demonstrated the probiotic potential of enterococcal consumption (e.g., gastrointestinal and respiratory disease, hyperlipidemia alleviation, as well as infection prevention)