p53 mediated cell cytotoxicity and DNA damage in lung cancer cell line A549 triggered by a small peptide extracted from a probiotic strain Lacticaseibacillus casei.
- 2026-03-13
- BMC biotechnology 26(1)
- Jannatul Firdous Siddique
- G R Shree Kumari
- Sudarshana Deepa Vijay Kumar
- C Subathra Devi
- Mohanasrinivasan Vaithilingam
- PubMed: 41826945
- DOI: 10.1186/s12896-026-01119-z
- Low evidence
qRT-PCR showed increased p53 and BAX, increased CASP8, downregulation of CASP7, and no significant change in CASP3.
- Effect
- Beneficial
- Effect size
- Moderate