Lacticaseibacillus casei and Reduced Macrophage Inflammatory Protein-1β Level

• A Double-Blind, Randomized Placebo-Controlled Trial of Probiotic Lactobacillus casei Shirota in Stable Cirrhotic Patients.

  • 2020-06-02
  • RCT
  • Nutrients 12(6)
  • • Jane Macnaughtan
    • Francesco Figorilli
    • Elisabet García-López
    • Haw Lu
    • Helen Jones
    • Rohit Sawhney
    • Kaori Suzuki
    • Sarah Fairclough
    • Joanne Marsden
    • Alba Moratella
    • I Jane Cox
    • Linda Thomas
    • Nathan Davies
    • Roger Williams
    • Raj Mookerjee
    • Gavin Wright
    • Rajiv Jalan

  • PubMed: 32498372
  • DOI: 10.3390/nu12061651

  9 Insights on

  • Reduced Macrophage Inflammatory Protein-1β Level

  • High evidence
  • Rigorous Journal
  • Clinical

  interleukin-17a and macrophage inflammatory protein-1β (non-alcoholic cirrhosis), compared with placebo.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  three times daily for six months