Lacticaseibacillus casei and Reduced Vertiginous Attack

Time to effect

Median: 4 months · IQR 4 months–4 months · Range 4 months–4 months — Reported in 1 of 1 study

Safety in these studies

Overall tolerabilityReported
Although placebo effect cannot be ignored in intervention for VM patients, the probiotic LcS still exhibits considerable efficacy against VM symptoms over a 4 month study period, supporting further clinical study of a larger and more diverse cohort.
from: The probiotic Lactobacillus casei Shirota attenuates symptoms of vestibular migraine: a ra

1 of 1 paper

The probiotic Lactobacillus casei Shirota attenuates symptoms of vestibular migraine: a randomised placebo-controlled double-blind clinical trial.

2020-09-01
RCT
Beneficial microbes 11(5)
- X Qi
- G Fan
- H Jia

PubMed: 32865025
DOI: 10.3920/bm2020.0058

6 Insights on

Reduced Vertiginous Attack

High evidence
Rigorous Journal
Clinical

The primary endpoints were vestibular symptoms, evaluated by the number of vertiginous attacks during the past week ... Efficacy of LcS over placebo was not obvious at 2 month follow-up. At 4 month follow-up, while both LcS and placebo groups of VM patients displayed alleviated symptoms, the extents of the improvements were significantly better in LcS group than those of placebo group, with regard to vestibular symptoms using DHI and VSS

Effect: Neutral
Effect size: Small
Significant: No