Efficacy and safety of Lacticaseibacillus paracasei Lpc-37® in students facing examination stress: A randomized, triple-blind, placebo-controlled clinical trial (the ChillEx study).
- 2023-10
- RCT
- Brain, behavior, & immunity - health 32
- Sanna M Mäkelä
- Síle M Griffin
- Jenni Reimari
- Kara C Evans
- Ashley A Hibberd
- Nicolas Yeung
- Alvin Ibarra
- Jouni Junnila
- Jari Turunen
- Ronnie Beboso
- Balgit Chhokar
- Timothy G Dinan
- John Cryan
- Elaine Patterson
- PubMed: 37662485
- DOI: 10.1016/j.bbih.2023.100673
- High evidence
A reduction in Bond Lader VAS-alertness was also demonstrated in the Lpc-37 group compared to placebo (estimate -3.97; 95% CI: -7.78, -0.15; p = 0.042) just prior to the examination.
- Effect
- Harmful
- Effect size
- Small
- Significant
- Yes