Efficacy and safety of Lacticaseibacillus rhamnosus R0011 and Lactobacillus helveticus R0052 as an adjuvant for Helicobacter pylori eradication: a double-blind, randomized, placebo-controlled study.
- 2023-09-14
- RCT · n = 160
- Frontiers in gastroenterology (Lausanne, Switzerland) 2
- Anya Kiattiweerasak
- Natsuda Aumpan
- Soonthorn Chonprasertsuk
- Bubpha Pornthisarn
- Sith Siramolpiwat
- Patommatat Bhanthumkomol
- Pongjarat Nunanan
- Navapan Issariyakulkarn
- Varocha Mahachai
- Yoshio Yamaoka
- Ratha-Korn Vilaichone
- PubMed: 41821821
- DOI: 10.3389/fgstr.2023.1245993
- High evidence
As per-protocol analysis, eradication rates after the 14-day regimen with probiotic or placebo were 90.9% and 75.0% (p=0.047), respectively.
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes