Lacticaseibacillus rhamnosus R0011 and Increased Mucosal Anti-Inflammatory Mediator MIF Production

• Lacticaseibacillus rhamnosus R0011 secretome attenuates Salmonella enterica serovar Typhimurium secretome-induced intestinal epithelial cell monolayer damage and pro-inflammatory mediator production in intestinal epithelial cell and antigen-presenting cell co-cultures

  • 2022-09-28
  • Frontiers in Microbiology 13
  • • M. Jeffrey
    • Chad W. MacPherson
    • T. Tompkins
    • J. Green-Johnson

  • PubMed: 36246229
  • DOI: 10.3389/fmicb.2022.980989

  6 Insights on

  • Increased Mucosal Anti-Inflammatory Mediator MIF Production

  • Low evidence
  • Clinical

  apically delivered LrS induces apical secretion of macrophage inhibitory factor (MIF)

  Effect

  Beneficial

  Effect size

  Small