Lactiplantibacillus plantarum 22A-3-induced TGF-β1 secretion from intestinal epithelial cells stimulated CD103+ DC and Foxp3+ Treg differentiation and amelioration of colitis in mice.
- 2022-01-07
- Clinical Trial
- Food & Function 12(17)
- Jarukan Lamubol
- Nobuaki Ohto
- Hiroshige Kuwahara
- M. Mizuno
- PubMed: 34282811
- DOI: 10.1039/d1fo00990g
- Low evidence
- Animal Study
Both the aldehyde dehydrogenase 1 family member A2 (Aldh1a2) mRNA expression and population of CD103+ dendritic cells (DCs) in the small intestine significantly increased in the LP22A3-treated group.
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes