Vaginal-Derived Potential Probiotics and Their Postbiotics Alleviate Aerobic Vaginitis via Suppressing TLR4/MyD88/NF-κB Signalling Pathway and Potentially Enhancing Vaginal Barrier.
- 2026-03
- Microbial biotechnology 19(3)
- Meiyun Tian
- Xinyi Zhang
- Xuan Xu
- Xia He
- Xiaoyun Wu
- Jing Wei
- Buzhen Tan
- Tingtao Chen
- PubMed: 41807990
- DOI: 10.1111/1751-7915.70327
- Low evidence
- Animal Study
Supplementation with L. crispatus YBR-01 and L. plantarum YBR-01, either individually or in combination, attenuated vaginal edema, reduced proinflammatory mediators, and restored anti-inflammatory cytokines, with the combination therapy yielding the best results.
- Effect
- Beneficial
- Effect size
- Moderate