Lactobacillus acidophilus L-92 and Detected Vaginal Colonization by Probiotic Strain

• Strain-specific qPCR assay to track the vaginal colonization of the probiotic Lacticaseibacillus rhamnosus TOM 22.8 strain orally administered.

  • 2025-11-17
  • Clinical Trial
  • BMC microbiology 25(1)
  • • Amanda Vaccalluzzo
    • Alessandra Pino
    • Georgiana Bosco
    • Cinzia Caggia
    • Cinzia Lucia Randazzo

  • PubMed: 41249926
  • DOI: 10.1186/s12866-025-04470-x

  2 Insights on

  • Detected Vaginal Colonization by Probiotic Strain

  • Moderate evidence

  the qPCR methodology allowed the detection of the Lacticaseibacillus rhamnosus TOM 22.8 probiotic strain in vaginal swab samples, with cell densities ranging from 5.24 log CFU/mL to 6.65 log CFU/mL

  Effect

  Beneficial

  Effect size

  Moderate