Lactobacillus acidophilus L-92 and Reduced Indoxyl Sulfate Levels

• Lactobacillus acidophilus KBL409 improves serum indoxyl sulfate via gut microbial changes in a human study.

  • 2026-02-16
  • RCT · n = 34
  • NPJ science of food 10(1)
  • • Sung Jae Jang
    • SungJun Park
    • Kiuk Lee
    • Woon-Ki Kim
    • Sung Hyun Moon
    • Bo-Ram Cho
    • Cheonghoon Lee
    • Hyungjin Lee
    • Tae-Wook Nam
    • GwangPyo Ko

  • PubMed: 41698905
  • DOI: 10.1038/s41538-026-00755-1

  1 Insight on

  • Reduced Indoxyl Sulfate Levels

  • High evidence

  After 16 weeks, the serum indoxyl sulfate (IS) concentration was significantly lower in the L. acidophilus KBL409 group than in the placebo group (p < 0.05).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes