Lactobacillus acidophilus L-92 and Reduced Inflammation Markers

• Alleviating effects of probiotic supplementation on biomarkers of inflammation and oxidative stress in non-communicable diseases: a systematic review and meta-analysis using the GRADE approach.

  • 2025-07-01
  • Meta-Analysis
  • BMC pharmacology & toxicology 26(1)
  • • Xiaoyuan Yu
    • Li Yan
    • Lingxiao Chen
    • Xianmei Shen
    • Wenzheng Zhang

  • PubMed: 40598607
  • DOI: 10.1186/s40360-025-00957-5

  5 Insights on

  • Reduced Inflammation Markers

  • High evidence

  probiotic supplementation significantly reduced CRP (SMD = -1.33, 95% CI: -1.84, -0.82; p < 0.001, high certainty), TNF-α (SMD = -1.10, 95% CI: -1.66, -0.55; p < 0.001, low certainty)

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes