Lactobacillus acidophilus L-92 and Reduced Thymus and Activation-Regulated Chemokine Level

• Additive effect of Lactobacillus acidophilus L-92 on children with atopic dermatitis concomitant with food allergy

  • 2019-04
  • RCT · n = 59
  • Asia Pacific Allergy 9(2)
  • • Joan Nakata
    • Tatsuhiko Hirota
    • Harue Umemura
    • T. Nakagawa
    • N. Kando
    • M. Futamura
    • Yasunori Nakamura
    • Komei Ito

  • PubMed: 31089460
  • DOI: 10.5415/apallergy.2019.9.e18

  7 Insights on

  • Reduced Thymus and Activation-Regulated Chemokine Level

  • High evidence
  • Rigorous Journal
  • Clinical

  Significant decreases in thymus and activation-regulated chemokine (TARC) and total IgE were also detected 24 weeks after intake in the L-92 group compared with the placebo group.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  20 mg L-92/day

• Effects of Oral Administration of Lactobacillus acidophilus L-92 on the Symptoms and Serum Markers of Atopic Dermatitis in Children

  • 2010-09-21
  • RCT
  • International Archives of Allergy and Immunology 154(3)
  • • S. Torii
    • Akiko Torii
    • K. Itoh
    • A. Urisu
    • A. Terada
    • T. Fujisawa
    • Kazue Yamada
    • Hiromi Suzuki
    • Y. Ishida
    • F. Nakamura
    • H. Kanzato
    • D. Sawada
    • A. Nonaka
    • M. Hatanaka
    • S. Fujiwara

  • PubMed: 20861645
  • DOI: 10.1159/000321110

  6 Insights on

  • Reduced Thymus and Activation-Regulated Chemokine Level

  • High evidence
  • Clinical

  L-92 also affected the serum concentrations of thymus and activation-regulated chemokine in a time-dependent manner.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes