Lactobacillus acidophilus LA-02 and Enhanced Tumor-Targeted Drug Delivery

• Bacteria-powered LA@CaDGP biomotor: a multi-modal weapon integrating calcium overload, chemotherapy, and starvation for breast cancer therapy.

  • 2026-01-06
  • Journal of nanobiotechnology 24(1)
  • • Jingrong Huang
    • Yongcheng Tang
    • Kewei Xiang
    • Biqiong Wang
    • Jia Wang
    • Yun Lu
    • Yue Li
    • Hongjun Deng
    • Tao Li
    • Kang Xiong
    • Qinglian Wen
    • Shaozhi Fu

  • PubMed: 41495746
  • DOI: 10.1186/s12951-025-03968-w

  1 Insight on

  • Enhanced Tumor-Targeted Drug Delivery

  • Low evidence

  we developed a novel bacteria-propelled biomotor system, designated as LA@CaDGP, to enhance the tumor-specific drug delivery

  Effect

  Beneficial

  Effect size

  Large