Lactobacillus acidophilus LA-02 and Reduced Anxiety

• Prebiotics, probiotics, and synbiotics and maternal mental health during pregnancy and postpartum period: a systematic review.

  • 2026-02-17
  • Systematic Review · n = 342
  • Frontiers in nutrition 13
  • • Sandra Martín-Peláez
    • Luis Miguel Martín-delosReyes
    • Naomi Cano-Ibáñez

  • PubMed: 41783815
  • DOI: 10.3389/fnut.2026.1776398

  4 Insights on

  • Reduced Anxiety

  • High evidence

  Two RCTs using Lactobacillus rhamnosus HN001, Limosilactobacillus reuteri PBS072 and Bifidobacterium breve reported small but significant reductions in depressive symptoms [Edinburgh Postnatal Depression Scale, MD = -1.2; 95% CI (-2.3, -0.1)] and anxiety symptoms [State-Trait Anxiety Inventory-6: MD = -1.0; 95% CI (-1.9, -0.2); p < 0.05)] during pregnancy.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes