Lactobacillus acidophilus LA85 and Improved Stool Consistency

• Efficacy and Safety of Lactobacillus acidophilus LA85 in Preventing Antibiotic-Associated Diarrhea: A Randomized, Placebo-Controlled Study.

  • 2025-06
  • RCT · n = 82
  • Food science & nutrition 13(6)
  • • Jianguo Zhu
    • Yukun Sun
    • Yao Dong
    • Yunjiao Zhao
    • Zhonghui Gai
    • Shuguang Fang

  • PubMed: 40548185
  • DOI: 10.1002/fsn3.70490

  6 Insights on

  • Improved Stool Consistency

  • High evidence

  Participants receiving LA85 exhibited less variability in stool consistency scores, assessed by the Bristol stool form scale (BSFS), maintaining scores consistently around 3.5. In contrast, placebo recipients had greater fluctuations between 3.5 and 4.0, indicating less stable stool consistency during antibiotic treatment.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  2×10^9 CFU/day