Lactobacillus acidophilus NCFM and Reduced Alpha-Synuclein Accumulation

• Neuroprotective effects of Bifidobacterium animalis HN019 and Lactobacillus acidophilus NCFM in MPTP-induced Parkinson's disease mice.

  • 2026-03
  • Brain, behavior, and immunity 133
  • • Chengjun Mo
    • Yiwei Qian
    • Yi Zhang
    • Xiaoqin He
    • Yiqiu Lai
    • Shaoqing Xu
    • Penghui Ai
    • Xiaodong Yang
    • Qin Xiao

  • PubMed: 41513011
  • DOI: 10.1016/j.bbi.2026.106257

  6 Insights on

  • Reduced Alpha-Synuclein Accumulation

  • Low evidence
  • Animal Study

  Furthermore, α-synuclein (α-Syn) overexpression was reduced in both the colon and SN.

  Effect

  Beneficial

  Effect size

  Moderate