Lactobacillus acidophilus NCFM and Reduced Beta-Defensin Level

• Probiotic cheese containing Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus NCFM® modifies subpopulations of fecal lactobacilli and Clostridium difficile in the elderly.

  • 2011-01-25
  • RCT
  • Age (Dordrecht, Netherlands) 34(1)
  • • Sampo J Lahtinen
    • Sofia Forssten
    • Juhani Aakko
    • Linda Granlund
    • Nina Rautonen
    • Seppo Salminen
    • Matti Viitanen
    • Arthur C Ouwehand

  • PubMed: 21264685
  • DOI: 10.1007/s11357-011-9208-6

  4 Insights on

  • Reduced Beta-Defensin Level

  • High evidence
  • Elderly

  No increase in fecal calprotectin and β-defensin concentrations suggests that the probiotic treatment did not affect intestinal inflammatory markers.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No