Probiotic effects on cold and influenza-like symptom incidence and duration in children.
- 2009-08-01
- RCT · n = 112
- Pediatrics 124(2)
- Gregory J Leyer
- Shuguang Li
- Mohamed E Mubasher
- Cheryl Reifer
- Arthur C Ouwehand
- PubMed: 19651563
- DOI: 10.1542/peds.2008-2666
- High evidence
- Large Human Trial
- Highly Cited
- Children
Fever, coughing, and rhinorrhea duration was decreased significantly, relative to placebo, by 32% (single strain; P = .0023) and 48% (strain combination; P < .001).
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- Twice daily for 6 months