Lactobacillus acidophilus NCFM and Reduced Rhinorrhea Incidence

• Probiotic effects on cold and influenza-like symptom incidence and duration in children.

  • 2009-08-01
  • RCT · n = 112
  • Pediatrics 124(2)
  • • Gregory J Leyer
    • Shuguang Li
    • Mohamed E Mubasher
    • Cheryl Reifer
    • Arthur C Ouwehand

  • PubMed: 19651563
  • DOI: 10.1542/peds.2008-2666

  8 Insights on

  • Reduced Rhinorrhea Incidence

  • High evidence
  • Large Human Trial
  • Highly Cited
  • Children

  Relative to the placebo group, single and combination probiotics reduced rhinorrhea incidence by 28.2% (P = .68) and 58.8% (P = .03), respectively.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  Twice daily for 6 months