Lactobacillus acidophilus R0418 and Reduced Ulcerative Colitis Symptoms

• Live Lactobacillus acidophilus alleviates ulcerative colitis via the SCFAs/mitophagy/NLRP3 inflammasome axis.

  • 2022-03-15
  • Clinical Trial
  • Food & Function 13(5)
  • • Pei Li
    • Guoping Chen
    • Jiaxian Zhang
    • Chaoying Pei
    • Ying Chen
    • Jing Gong
    • S. Deng
    • Kaiwei Cai
    • Haiyan Li
    • Dawei Wang
    • Baochun Shen
    • Zhiyong Xie
    • Q. Liao

  • PubMed: 35195119
  • DOI: 10.1039/d1fo03360c

  13 Insights on

  • Reduced Ulcerative Colitis Symptoms

  • Low evidence
  • Animal Study

  compared with the heat-killed L. acidophilus and the culture supernatant of L. acidophilus, the live L. acidophilus (La) has the optimal therapeutic effect on UC rats.

  Effect

  Beneficial

  Effect size

  Large