Lactobacillus acidophilus and Alleviated Depression

• Depression-associated gut microbes, metabolites and clinical trials.

  • 2024-01-31
  • Review
  • Frontiers in microbiology 15
  • • Meiling Wang
    • Zhaoqi Song
    • Shirong Lai
    • Furong Tang
    • Lijun Dou
    • Fenglong Yang

  • PubMed: 38357350
  • DOI: 10.3389/fmicb.2024.1292004

  1 Insight on

  • Alleviated Depression

  • Low evidence

  we extensively detail the correlation between gut microbiota, including Lactobacillus acidophilus and Bifidobacterium longum, and metabolites such as short-chain fatty acids (SCFAs) and 5-hydroxytryptamine (5-HT) concerning depression. Furthermore, we delve into the potential health benefits of microbiome-targeted therapies, encompassing probiotics, prebiotics, and synbiotics, in alleviating depression.

  Effect

  Beneficial

  Effect size

  Small