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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Lactobacillus acidophilus and Improved Overall Survival

Doses used in studies

mg/day: 1,500 (median 1,500, IQR 1,500–1,500) — 1 study

Time to effect

Median: 3 months · IQR 3 months–3 months · Range 3 months–3 months — Reported in 1 of 1 study

1 of 1 paper

Expanding CYLD protein in NF-κβ/TNF-α signaling pathway in response to Lactobacillus acidophilus in non-metastatic rectal cancer patients.
- 2023-09-19
- RCT
- Medical oncology (Northwood, London, England) 40(10)
- - Farhad Zamani
  - Solmaz Khalighfard
  - Mohammad Reza Kalhori
  - Amirhoushang Poorkhani
  - Taghi Amiriani
  - Payam Hosseinzadeh
  - Ebrahim Esmati
  - Mahdi Alemrajabi
  - Alireza Nikoofar
  - Fahimeh Safarnezhad Tameshkel
  - Ali Mohammad Alizadeh
- PubMed: 37725175
- DOI: 10.1007/s12032-023-02170-y
1 Insight on
- Improved Overall Survival
- High evidence
- Clinical
A higher overall survival rate was seen after L. acidophilus consumption compared to the placebo group (P < 0.05).
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
500 mg three times daily