Lactobacillus acidophilus and Reduced Seizure Frequency

• Probiotic Supplementation as an Adjuvant Therapy in Pediatric Drug-Resistant Epilepsy: A Double-Blind Placebo-Controlled Trial.

  • 2026-03-01
  • RCT · n = 60
  • Pharmacotherapy 46(3)
  • • Amira R Rashdan
    • Sahar M El-Haggar
    • Ahmed Mustafa Kishk
    • Tarek M Mostafa

  • PubMed: 41693686
  • DOI: 10.1002/phar.70117

  6 Insights on

  • Reduced Seizure Frequency

  • High evidence
  • Clinical

  the probiotic (Lactobacillus acidophilus) group experienced a significant decline in seizure frequency (p = 0.04)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  daily probiotic (Lactobacillus acidophilus) supplement