Lactobacillus amylovorus and Improved Growth Performance

Research synthesisLow evidenceModerate effect4 studies · 4 beneficial · 0 neutral · 0 harmful

Across 4 studies, all reported beneficial effects of Lactobacillus amylovorus on growth performance, with 3 reaching statistical significance. Effect sizes ranged from small to large, with a predominance of moderate effects. The limited evidence base primarily involves animal models (weaning pigs, IUGR piglets/mice, Asian seabass, weaned lambs), and no consistent dose or duration data are available.

Studied populations: weaning pigs, intrauterine growth restricted (IUGR) piglets and mice, Asian seabass fingerlings, weaned lambs

Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Evidence base is small (only 4 studies) — conclusions should be considered preliminary. All studies are in animal models; applicability to human growth performance is unknown.

Generated May 12, 2026

4 of 4 papers

Transcriptome and microbiota analysis reveal differences in the cecum of weaning pigs in response to different dietary crude protein levels.
- 2026-01-01
- RCT
- Animal bioscience 39(1)
- - Yu-Hsiang Yu
  - Sheng-Bing Chen
  - Han-Tsung Wang
  - Chuan-Shun Lin
  - Andrzej Dybus
  - Beata Hukowska-Szematowicz
  - Yi-Hung Li
- PubMed: 40808558
- DOI: 10.5713/ab.25.0135
2 Insights on
- Improved Growth Performance
- High evidence
The abundance of L. amylovorus DSM 20531 was significantly greater in the M group than in the other groups (p≤0.05). The abundance of L. amylovorus DSM 20531 was positively correlated with growth performance.
Effect
Beneficial
Effect size
Small
Significant
Yes
Lactobacillus amylovorus Promotes Lactose Utilization in Small Intestine and Enhances Intestinal Barrier Function in Intrauterine Growth Restricted Piglets.
- 2024-02
- Clinical Trial
- The Journal of nutrition 154(2)
- - Yujun Wu
  - Xiaoyi Liu
  - Youwei Zou
  - Xiangyu Zhang
  - Zhenyu Wang
  - Jie Hu
  - Dandan Han
  - Jinbiao Zhao
  - Zhaolai Dai
  - Junjun Wang
- PubMed: 38072153
- DOI: 10.1016/j.tjnut.2023.12.004
3 Insights on
- Improved Growth Performance
- Moderate evidence
L. amylovorus Mafic1501 elevated body weight and average daily gain of IUGR mice and piglets (P < 0.05).
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Combinatorial supplementation of fish feeds enhanced growth performance and disease resilience in aquaculture.
- 2026-03-08
- Journal of animal science and biotechnology 17(1)
- - The-Thien Tran
  - Manish Mahotra
  - Kaarunya Sampathkumar
  - Wenrui Li
  - Hong Yu
  - Ling Xin Yong
  - Li Ling Tan
  - Mingyue Sun
  - Patricia Lynne Conway
  - Say Chye Joachim Loo
- PubMed: 41794794
- DOI: 10.1186/s40104-026-01357-3
2 Insights on
- Improved Growth Performance
- Low evidence
Feeding trials showed that encapsulated probiotics increased body weight by 33% compared with controls.
Effect
Beneficial
Effect size
Large
Gut microbiota-driven IL-17/PPAR axis mediates epigallocatechin-induced intestinal repair in weaned lambs.
- 2026-04-04
- Journal of animal science and biotechnology 17(1)
- - Yuwei Zhao
  - Zhuo Wang
  - Dingkun Fan
  - Jixian Zhang
  - Yan Tu
  - Qiyu Diao
  - Kai Cui
- PubMed: 41933424
- DOI: 10.1186/s40104-026-01371-5
5 Insights on
- Improved Growth Performance
- Low evidence
Supplementation with 12.5 mg/kg EGC (LE) significantly improved growth performance, reduced diarrhea incidence (P < 0.05), enhanced mucosal antioxidant capacity (P < 0.001), and strengthened anti-inflammatory ability (P < 0.001).
Effect
Beneficial
Effect size
Moderate
Significant
Yes

Lactobacillus amylovorus and Improved Growth Performance

Transcriptome and microbiota analysis reveal differences in the cecum of weaning pigs in response to different dietary crude protein levels.

Lactobacillus amylovorus Promotes Lactose Utilization in Small Intestine and Enhances Intestinal Barrier Function in Intrauterine Growth Restricted Piglets.

Combinatorial supplementation of fish feeds enhanced growth performance and disease resilience in aquaculture.

Gut microbiota-driven IL-17/PPAR axis mediates epigallocatechin-induced intestinal repair in weaned lambs.