Lactobacillus amylovorus and Reduced Intestinal Tissue Injury

• Probiotic-derived extracellular vesicles alleviate AFB1-induced intestinal injury by modulating the gut microbiota and AHR activation.

  • 2024-11-11
  • Journal of nanobiotechnology 22(1)
  • • Jinyan Li
    • Mengdie Shi
    • Yubo Wang
    • Jinyan Liu
    • Shuiping Liu
    • Weili Kang
    • Xianjiao Liu
    • Xingxiang Chen
    • Kehe Huang
    • Yunhuan Liu

  • PubMed: 39529091
  • DOI: 10.1186/s12951-024-02979-3

  4 Insights on

  • Reduced Intestinal Tissue Injury

  • Low evidence
  • Animal Study

  LA.EVs significantly alleviated AFB1-induced intestinal injury by inhibiting the production of proinflammatory cytokines, decreasing intestinal permeability and increasing the expression of tight junction proteins.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes