Lactobacillus amylovorus Inhibits the TLR4 Inflammatory Signaling Triggered by Enterotoxigenic Escherichia coli via Modulation of the Negative Regulators and Involvement of TLR2 in Intestinal Caco-2 Cells and Pig Explants
- 2014-04-14
- PLoS ONE 9(4)
- A. Finamore
- Marianna Roselli
- Ambra Imbinto
- Julie Seeboth
- I. Oswald
- E. Mengheri
- PubMed: 24733511
- DOI: 10.1371/journal.pone.0094891
- Moderate evidence
- Highly Cited
- Rigorous Journal
- Mixed
L. amylovorus suppress the activation of the different steps of TLR4 signaling in Caco-2/TC7 cells and pig explants... The immunofluorescence analysis confirms the lack of phospho-p65 translocation into the nucleus.
- Effect
- Beneficial
- Effect size
- Moderate