Lactobacillus amylovorus and Reduced Rotavirus Infection Severity

• A strain of Lactobacillus plantarum from piglet intestines enhances the anti-PoRV effect via the STING-IFN-I pathway.

  • 2025-05-03
  • BMC veterinary research 21(1)
  • • Anqi Sun
    • Xin Shan
    • Ruihan Liu
    • Zhengxu Tang
    • Jingshu Huang
    • Shihan Zhang
    • Lihong Bian
    • Yumeng Shi
    • Zixuan Liu
    • Jingtao Hu
    • Chunfeng Wang

  • PubMed: 40319282
  • DOI: 10.1186/s12917-025-04766-0

  3 Insights on

  • Reduced Rotavirus Infection Severity

  • Low evidence
  • Animal Study

  LP1 exerts potent anti-PoRV activity in both murine models and porcine intestinal epithelial (IPEC-J2) cells through STING-IRF3 signaling axis-mediated IFN-β production.

  Effect

  Beneficial

  Effect size

  Large