Lactobacillus brevis MAK11L82B and Enhanced Immunoregulatory Molecule Activity

• GABA potentiate the immunoregulatory effects of Lactobacillus brevis BGZLS10-17 via ATG5-dependent autophagy in vitro

  • 2020-01-28
  • Scientific Reports 10(1)
  • • S. S. Bajić
    • Jelena Đokić
    • M. Dinić
    • S. Tomić
    • N. Popović
    • Emilija Brdarić
    • N. Golić
    • M. Tolinački

  • PubMed: 31992761
  • DOI: 10.1038/s41598-020-58177-2

  4 Insights on

  • Enhanced Immunoregulatory Molecule Activity

  • Low evidence
  • Rigorous Journal

  At the other hand, GABA-containing supernatants displayed the strongest stimulatory effects on the expression of immunoregulatory molecules, such as Foxp3+, IL-10, TGF-β, CTLA4 and SIRP-α.

  Effect

  Beneficial

  Effect size

  Moderate