Lactobacillus brevis MAK11L82B and Reduced Gingival Bleeding

• Probiotic strains of Lactobacillus brevis and Lactobacillus plantarum as adjunct to non-surgical periodontal therapy: 3-month results of a randomized controlled clinical trial

  • 2020-07-14
  • RCT · n = 40
  • Clinical Oral Investigations 25(3)
  • • P. Pudgar
    • K. Povšič
    • K. Čuk
    • K. Seme
    • M. Petelin
    • R. Gašperšič

  • PubMed: 32666349
  • DOI: 10.1007/s00784-020-03449-4

  5 Insights on

  • Reduced Gingival Bleeding

  • High evidence
  • Clinical

  The logistic regression showed higher odds for the healing of gingival bleeding (OR = 2.12, p = 0.048) in the probiotic group.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

• Effect of Lactobacillus brevis CD2 containing lozenges and plaque pH and cariogenic bacteria in diabetic children: a randomised clinical trial

  • 2020-10-21
  • RCT · n = 8
  • Clinical Oral Investigations 25(1)
  • • S. Lai
    • P. Lingström
    • M. Cagetti
    • F. Cocco
    • G. Meloni
    • M. Arrica
    • G. Campus

  • PubMed: 33083852
  • DOI: 10.1007/s00784-020-03342-0

  5 Insights on

  • Reduced Gingival Bleeding

  • High evidence

  Bleeding score decreased significantly in both groups, showing a statistically significant lower bleeding score at t2 in the probiotic group (25.6%, 95% CI 21.5-32.7 vs 29.5%, 95% CI 25.2-34.9, p = 0.02).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes