Effect of Lactobacillus brevis CD2 containing lozenges and plaque pH and cariogenic bacteria in diabetic children: a randomised clinical trial
- 2020-10-21
- RCT · n = 8
- Clinical Oral Investigations 25(1)
- S. Lai
- P. Lingström
- M. Cagetti
- F. Cocco
- G. Meloni
- M. Arrica
- G. Campus
- PubMed: 33083852
- DOI: 10.1007/s00784-020-03342-0
- High evidence
In the probiotic group, Streptococcus mutans bacterial density mean scores dropped from 3.11 ± 1.13 at baseline to 1.82 ± 0.72 (t2) and to 2.06 ± 0.56 (t3), while in the placebo group, the scores were 3.09 ± 0.8 (t0), 2.82 ± 0.47 (t2) and 3.11 ± 0.43 (t3) (p < 0.01).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes