Lactobacillus brevis SBC8803 and Improved Mucosal Healing

• Long-Chain Polyphosphate Is a Potential Agent for Inducing Mucosal Healing of the Colon in Ulcerative Colitis.

  • 2019-11-20
  • Clinical Trial
  • Clinical pharmacology and therapeutics 107(2)
  • • Mikihiro Fujiya
    • Nobuhiro Ueno
    • Shin Kashima
    • Kazuyuki Tanaka
    • Aki Sakatani
    • Katsuyoshi Ando
    • Kentaro Moriichi
    • Hiroaki Konishi
    • Naoya Kamiyama
    • Yoshikazu Tasaki
    • Tomohiro Omura
    • Kazuo Matsubara
    • Masaki Taruishi
    • Toshikatsu Okumura

  • PubMed: 31513280
  • DOI: 10.1002/cpt.1628

  2 Insights on

  • Improved Mucosal Healing

  • Moderate evidence

  Long-chain polyphosphate is a potential agent for inducing mucosal healing of the colon in ulcerative colitis.

  Effect

  Beneficial

  Effect size

  Large

• Modulation of Stem Cell Progeny by Probiotics during Regeneration of Gastric Mucosal Erosions.

  • 2021-06-28
  • Biology 10(7)
  • • Farah Al-Yassir
    • Ghalia Khoder
    • Subi Sugathan
    • Prashanth Saseedharan
    • Asma Al Menhali
    • Sherif M Karam

  • PubMed: 34203400
  • DOI: 10.3390/biology10070596

  3 Insights on

  • Improved Mucosal Healing

  • Low evidence

  mice that received probiotics before or after the induction of erosion showed a decrease in erosion index with an increase in gastric epithelial stem/progenitor cell proliferation and enhanced production of mucus, trefoil factors, and ghrelin... These mice also showed restoration of the amount of H+,K+-ATPase and pepsinogen

  Effect

  Beneficial

  Effect size

  Moderate