Probiotic-Derived Polyphosphate Accelerates Intestinal Epithelia Wound Healing through Inducing Platelet-Derived Mediators.
- 2021-01
- Mediators of inflammation 2021(1)
- Shotaro Isozaki
- Hiroaki Konishi
- Mikihiro Fujiya
- Hiroki Tanaka
- Yuki Murakami
- Shin Kashima
- Katsuyoshi Ando
- Nobuhiro Ueno
- Kentaro Moriichi
- Toshikatsu Okumura
- PubMed: 33859537
- DOI: 10.1155/2021/5582943
- Low evidence
- Animal Study
The supernatant of poly P-treated PRP, but not poly P itself, accelerated wound healing... platelet-derived mediators induced by poly P improved intestinal inflammation through the promotion of epithelial cell growth by the activation of the ERK signaling pathway.
- Effect
- Beneficial
- Effect size
- Moderate