Lactobacillus brevis SBC8803 and Maintained Remission in Ulcerative Colitis

• Long-Chain Polyphosphate Is a Potential Agent for Inducing Mucosal Healing of the Colon in Ulcerative Colitis.

  • 2019-11-20
  • Clinical Trial
  • Clinical pharmacology and therapeutics 107(2)
  • • Mikihiro Fujiya
    • Nobuhiro Ueno
    • Shin Kashima
    • Kazuyuki Tanaka
    • Aki Sakatani
    • Katsuyoshi Ando
    • Kentaro Moriichi
    • Hiroaki Konishi
    • Naoya Kamiyama
    • Yoshikazu Tasaki
    • Tomohiro Omura
    • Kazuo Matsubara
    • Masaki Taruishi
    • Toshikatsu Okumura

  • PubMed: 31513280
  • DOI: 10.1002/cpt.1628

  2 Insights on

  • Maintained Remission in Ulcerative Colitis

  • Moderate evidence

  The first-in-human trial showed that 7 of the 10 enrolled patients acquired clinical remission, 4 of whom achieved endoscopic remission despite a history of treatment with anti-tumor necrosis factor (TNF)-α agents.

  Effect

  Beneficial

  Effect size

  Large